Pandemic threats are increasing as globalization, urbanization, and encroachment on animal habitats cause infectious outbreaks to become more frequent and severe. It is imperative that the United States build a pipeline of medical countermeasure development, beginning with basic scientific research and culminating in approved therapies. This report assesses preparedness for families of viral pathogens of pandemic potential and offers recommendations for steps the U.S. government can take to prepare for future pandemics.

China’s government has pushed the country’s technology and financial firms to expand abroad, and Southeast Asia’s growing economies — and AI companies — offer promising opportunities. This report examines the scope and nature of Chinese investment in the region. It finds that China currently plays a limited role in Southeast Asia’s emerging AI markets outside of Singapore and that Chinese investment activity still trails behind that of the United States. Nevertheless, Chinese tech companies, with support from the Chinese government, have established a broad range of other AI-related linkages with public and commercial actors across Southeast Asia.

CSET's Dr. Caroline Schuerger, Dr. Steph Batalis, and Vikram Venkatram submitted this comment with recommendations for the National Biotechnology and Biomanufacturing Initiative.

Biosafety Level-3 laboratories (BSL-3) are an essential part of research infrastructure and are used to develop vaccines and therapies. The research conducted in them provides insights into host-pathogen interactions that may help prevent future pandemics. However, these facilities also potentially pose a risk to society through lab accidents or misuse. Despite their importance, there is no comprehensive list of BSL-3 facilities, or the institutions in which they are housed. By systematically assessing PubMed articles published in English from 2006-2021, this paper maps institutions that host BSL-3 labs by their locations, augmenting current knowledge of where high-containment research is conducted globally.

China is banking on applying AI to biotechnology research in order to transform itself into a “biotech superpower.” In pursuit of that goal, it has emphasized bringing together different aspects of the development cycle to foster multidisciplinary research. This data brief examines the emerging trend of co-location of AI and biotechnology researchers and explores the potential impact it will have on this growing field.

Through the Quad forum, the United States, Australia, Japan and India have committed to pursuing an open, accessible and secure technology ecosystem and offering a democratic alternative to China’s techno-authoritarian model. This report assesses artificial intelligence collaboration across the Quad and finds that while Australia, Japan and India each have close AI-related research and investment ties to both the United States and China, they collaborate far less with one another.

CSET Research Fellow Caroline Schuerger testified before the Bipartisan Commission on Biodefense hearing on "The Biological Threat Expanse" Current and Future Challenges to National Biodefense." She discussed threats to the bioeconomy and steps the U.S. and its allies can take to harness biotechnology's capabilities and raise awareness of risky research.

Allies of the United States have begun to develop their own policy approaches to responsible military use of artificial intelligence. This issue brief looks at key allies with articulated, emerging, and nascent views on how to manage ethical risk in adopting military AI. The report compares their convergences and divergences, offering pathways for the United States, its allies, and multilateral institutions to develop common approaches to responsible AI implementation.

The Department of Defense can already begin applying its existing international science and technology agreements, global scientific networks, and role in multilateral institutions to stimulate digital defense cooperation. This issue brief frames this collection of options as a military AI cooperation toolbox, finding that the available tools offer valuable pathways to align policies, advance research, development, and testing, and to connect personnel–albeit in more structured ways in the Euro-Atlantic than in the Indo-Pacific.

With its massive information technology workforce, thriving research community and a growing technology ecosystem, India has a significant stake in the development of artificial intelligence globally. Drawing from a variety of original CSET datasets, the authors evaluate India’s potential for AI by examining its progress across five categories of indicators pertinent to AI development: talent, research, patents, companies and investments, and compute.