CSET submitted the following comment in response to a Request for Information (RFI) from the White House's Office of Science and Technology Policy about potential changes to the Policies for Federal and Institutional Oversight of Life Sciences Dual Use Research of Concern (DURC) and Recommended Policy Guidance for Departmental Development of Review Mechanisms for Potential Pandemic Pathogen Care and Oversight (P3CO).

This explainer overviews techniques to produce smaller and more efficient language models that require fewer resources to develop and operate. Importantly, information on how to leverage these techniques, and many of the subsequent small models, are openly available online for anyone to use. The combination of both small (i.e., easy to use) and open (i.e., easy to access) could have significant implications for artificial intelligence development.

Translation Snapshots are short posts that highlight related translations produced by CSET’s in-house translation team. Each snapshot identifies relevant translations, provides short summaries, and links to the full translations. Check back regularly for additional Translation Snapshots highlighting our work.

Gain- and loss-of-function research have contributed to breakthroughs in vaccine development, genetic research, and gene therapy. At the same time, a subset of gain- and loss-of-function studies involve high-risk, highly virulent pathogens that could spread widely among humans if deliberately or unintentionally released. In this report, we map the gain- and loss-of-function global research landscape using a quantitative approach that combines machine learning with subject-matter expert review.

Artificial intelligence that makes news headlines, such as ChatGPT, typically runs in well-maintained data centers with an abundant supply of compute and power. However, these resources are more limited on many systems in the real world, such as drones, satellites, or ground vehicles. As a result, the AI that can run onboard these devices will often be inferior to state of the art models. That can affect their usability and the need for additional safeguards in high-risk contexts. This issue brief contextualizes these challenges and provides policymakers with recommendations on how to engage with these technologies.

Foundation models could eventually introduce several pathways for undermining state security: accidents, inadvertent escalation, unintentional conflict, the proliferation of weapons, and the interference with human diplomacy are just a few on a long list. The Confidence-Building Measures for Artificial Intelligence workshop hosted by the Geopolitics Team at OpenAI and the Berkeley Risk and Security Lab at the University of California brought together a multistakeholder group to think through the tools and strategies to mitigate the potential risks introduced by foundation models to international security.

CSET submitted the following comment in response to a Request for Information (RFI) from the National Science Foundation (NSF) about the development of the newly established Technology, Innovation, and Partnerships (TIP) Directorate, in accordance with the CHIPS and Science Act of 2022.

Jenny Jun's testimony before the House Foreign Affairs Subcommittee on Indo-Pacific for a hearing titled, "Illicit IT: Bankrolling Kim Jong Un."

The current AI-for-cybersecurity paradigm focuses on detection using automated tools, but it has largely neglected holistic autonomous cyber defense systems — ones that can act without human tasking. That is poised to change as tools are proliferating for training reinforcement learning-based AI agents to provide broader autonomous cybersecurity capabilities. The resulting agents are still rudimentary and publications are few, but the current barriers are surmountable and effective agents would be a substantial boon to society.

Vaccines keep the U.S. public healthy while safeguarding economic stability and biosecurity. This report assesses the domestic vaccine manufacturing landscape and identifies two major vulnerabilities: a reliance on foreign manufacturers and a lack of manufacturing redundancy. Maintaining a resilient vaccine supply will require the U.S. government to take steps to protect the existing supply, identify and monitor manufacturing vulnerabilities, and create a stronger domestic production base.