CSET's Anna Puglisi was cited in an article by CNN that delves into China's efforts to become a global leader in the biosciences by investing billions of dollars and collecting vast amounts of genetic data from its 1.4 billion population.
Steph Batalis, Caroline Schuerger, and Vikram Venkatram
| June 16, 2023
Steph Batalis, Caroline Schuerger and Vikram Venkatram explore three notable areas in the life sciences where LLMs are catalyzing meaningful advances: drug discovery, genetics, and precision medicine.
Vaccines keep the U.S. public healthy while safeguarding economic stability and biosecurity. This report assesses the domestic vaccine manufacturing landscape and identifies two major vulnerabilities: a reliance on foreign manufacturers and a lack of manufacturing redundancy. Maintaining a resilient vaccine supply will require the U.S. government to take steps to protect the existing supply, identify and monitor manufacturing vulnerabilities, and create a stronger domestic production base.
Caroline Schuerger, Steph Batalis, Katherine Quinn, Amesh Adalja, and Anna Puglisi
| April 2023
Pandemic threats are increasing as globalization, urbanization, and encroachment on animal habitats cause infectious outbreaks to become more frequent and severe. It is imperative that the United States build a pipeline of medical countermeasure development, beginning with basic scientific research and culminating in approved therapies. This report assesses preparedness for families of viral pathogens of pandemic potential and offers recommendations for steps the U.S. government can take to prepare for future pandemics.
CSET Director of Biotechnology Programs and Senior Fellow Anna Puglisi provided insights into China's illicit efforts to acquire genetic data from the United States in Politico's Morning Cybersecurity. She pointed out that such data will serve a wide variety of interests, from health care to agriculture. “It’s enablers like sequencing and other tools of discovery that are going to drive the bioeconomy, that are going to drive precision medicine,” she said. “The more data you have, the more you can start to understand what genes do.”
Caroline Schuerger, Steph Batalis, and Vikram Venkatram
| January 20, 2023
CSET's Dr. Caroline Schuerger, Dr. Steph Batalis, and Vikram Venkatram submitted this comment with recommendations for the National Biotechnology and Biomanufacturing Initiative.
CSET hosted a discussion with Dr. Amesh Adalja, Senior Scholar at the Johns Hopkins University Center for Health Security, on the importance of understanding the breadth and depth of global biological activity in preparing for future pandemics.
Caroline Schuerger, Sara Abdulla, and Anna Puglisi
| August 2022
Biosafety Level-3 laboratories (BSL-3) are an essential part of research infrastructure and are used to develop vaccines and therapies. The research conducted in them provides insights into host-pathogen interactions that may help prevent future pandemics. However, these facilities also potentially pose a risk to society through lab accidents or misuse. Despite their importance, there is no comprehensive list of BSL-3 facilities, or the institutions in which they are housed. By systematically assessing PubMed articles published in English from 2006-2021, this paper maps institutions that host BSL-3 labs by their locations, augmenting current knowledge of where high-containment research is conducted globally.
China is banking on applying AI to biotechnology research in order to transform itself into a “biotech superpower.” In pursuit of that goal, it has emphasized bringing together different aspects of the development cycle to foster multidisciplinary research. This data brief examines the emerging trend of co-location of AI and biotechnology researchers and explores the potential impact it will have on this growing field.
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